S-100 Immunostaining for Differentiating Leprosy from other Granulomatous Lesions of Skin
نویسندگان
چکیده
منابع مشابه
Langerhans Cells in Skin Lesions of Leprosy
Background: Langerhans cells are important in the pathogenesis of leprosy. A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...
متن کاملGranulomatous lesions of the skin
Correspondence: Dr. Keyoor Gautam, MD Department of Pathology, Nepal Medical College, Kathmandu, Nepal Email: [email protected] Background: Granulomatous skin lesions often present as a diagnostic challenge to dermatopathologists due to various modes of presentation and identical histological picture produced by several causes. The aim of the study was to study different granulomatous skin l...
متن کاملProtein S-100 immunostaining as a diagnostic tool for DMBA-induced melanotic lesions.
In the present study we demonstrate immunohistochemically the presence of S-100 protein in numerous melanotic and amelanotic lesions (benign, premalignant and malignant) induced in albino guinea-pigs on topical application of the carcinogen. Positive staining was also present in all their amelanotic metastases. We reiterate the value of this stain in the diagnosis of melanomas, in particular am...
متن کاملlangerhans cells in skin lesions of leprosy
background: langerhans cells are important in the pathogenesis of leprosy. a recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. objective: to investigate a possible relationship between the number of langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. methods: an immunohistochemical staining for s100 ...
متن کاملHistopathology of skin lesions in leprosy.
INTRODUCTION Histopathological examination of skin or nerve biopsies or the demonstration of lepra bacilli in skin smears are the only laboratory means of confirming a diagnosis of leprosy.' The histological features are particularly useful in the early stages when there i s a sparsity of bacilli in skin smears. The histological changes in the skin in leprosy are p r ~ t e a n , ~ ~ and it is e...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology: Research and Practice
سال: 2020
ISSN: 2278-148X,2455-5320
DOI: 10.21088/ijprp.2278.148x.9220.6